SCRUM does not work. Agile is another buzzword. Having SCRUM implemented for distributed teams is like trekking on Hua Shan trail. Really?! Is SCRUM just about a board and a collection of meetings? Let me share my experience from leading distributed teams and walk you through the important aspects of agile that people often misses. I will describe the key elements of work environment, including people, roles, events, etc, where distributed teams spread across the globe work successfully using SCRUM for a complex biotechnology domain.